General Cell Based Assays
10X Genomics Inc GEM-X Flex Gene Expression Mouse 16-plex, 64 samples
GEM-X Flex Gene Expression Mouse 16-plex, 64 samples
Molecular Devices FLIPR Calcium Assay Kit, 2-Plate Sample, Fluorescence, Homogeneous
Sample kit for performing fluorescence-based intracellular calcium flux assays. The reagents are formulated for a homogeneous mix-and-read workflow to accelerate assay development and screening of GPCR and ion channel targets on compatible instruments.
- Sample kit containing two Component A vials, each sufficient for one microplate.
- Fluorescence-based, homogeneous assay format for calcium flux detection.
- Optimized for GPCR and ion channel screening and pharmacology studies.
- Compatible with common FLIPR and plate reader systems, including Tetra, Penta, and FlexStation platforms.
- Component B dilution/assay buffer is sold separately and required for some kit sizes.
Eurofins Discoverx PathHunter GLP1 (7-37) Bioassay Kit, 10-Plate. (93-0300Y2-00028)
The PathHunter GLP1 (7-37) Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses GLP1 (7-37) based activation of GLP1R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GLP1R and EA-tagged β-Arrestin-2. Activation of GLP1R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx InCELL Hunter eXpress CLK1 Kinase Binding Assay, 10pl Kit. (96-0059E1CP0L)
The InCELL Hunter eXpress CLK1 Kinase Binding Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with kinases. This kit assesses compound-engagement-based stabilization of CLK1 via detection of CLK1 levels. This product uses EFC technology. The cell line included overexpresses CLK1 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
10X Genomics Inc GEM-X Flex Gene Expression Mouse 16-plex, 64 samples
GEM-X Flex Gene Expression Mouse 16-plex, 64 samples
Eurofins Discoverx PathHunter eXpress GLP1R Activated GPCR Internalization Assay, 2pl Kit. (93-0724E3CP0M)
The PathHunter GLP1R Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of GLP1R via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged GLP1R. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting GLP1R-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical GlycolysIs asy Cofactr 250uL
Source Active recombinant MERS-CoV C-terminal His-tagged spike glycoprotein S1 subunit expressed in HEK293 cells Amino Acids 18-725 Tag C-terminal His MW 79.9 kDa
Medchemexpress LLC Tau tracer 2 (Pl-2620) | 2173361-80-1 | 99.9% | 264.26 | C15H9FN4 | 5 MG
Tau tracer 2 (Pl-2620) is a small-molecule PET imaging tracer that binds aggregated Tau protein for preclinical and diagnostic research into tauopathies such as Alzheimer's disease. Supplied as an off-white to light-yellow solid, it offers high purity and established solubility and storage profiles for reliable experimental use.
- High purity (99.92%).
- Suitable for PET imaging of tau aggregates in preclinical studies.
- Off-white to light-yellow solid, easy handling.
- Documented solubility in DMSO and recommended in vivo formulations.
- Long-term storage stability as powder at -20°C and 4°C.
- Available in small laboratory pack sizes for research use.
Eurofins Discoverx PathHunter eXpress mGCGR CHO-K1 β-Arrestin-1 GPCR Assay, 2-Plate Kit. (93-0973E2MCP2M)
The PathHunter mGCGR (ARR1) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. glucagon) based activation of mGCGR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mGCGR and EA-tagged β-Arrestin-1. Activation of mGCGR stimulates the recruitment of β-Arrestin-1 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress PTHR1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0315E2CP0L)
The PathHunter PTHR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. PTH) based activation of PTHR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PTHR1 and EA-tagged β-Arrestin-2. Activation of PTHR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cell Signaling Technology FastScan ELISA Kit, Total p44/42 MAPK, 480 Assays
The FastScan™ Total p44/42 MAPK (Erk1/2) ELISA Kit is a sandwich enzyme-linked immunosorbent assay designed to detect endogenous levels of p44/42 MAPK (Erk1/2) in human, mouse, rat, and monkey samples. The assay utilizes a capture antibody conjugated with a proprietary tag and an HRP-linked detection antibody, forming a sandwich complex immobilized to the plate via an anti-tag antibody. The resulting signal magnitude is proportional to the target protein quantity.
- Validated for use with human, mouse, rat, and monkey samples
- Features a streamlined sandwich ELISA protocol
- Includes optimized capture and detection antibodies in custom formulations
- Designed for high-sensitivity detection of total p44/42 MAPK
- Compatible with plate-based colorimetric detection at 450 nm
Eurofins Discoverx cAMP Hunter eXpress DRD5 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0094E2CP2L)
The cAMP Hunter DRD5 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. dopamine) based activation of DRD5 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type DRD5, a naturally Gs coupled GPCR. Upon activation of DRD5, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR65 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0428E2ACP1M)
The PathHunter GPR65 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR65 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR65 and EA-tagged β-Arrestin-2. Activation of GPR65 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR176 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0382E2ACP1M)
The PathHunter GPR176 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR176 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR176 and EA-tagged β-Arrestin-2. Activation of GPR176 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.